应用运动后踝臂指数评估冠心病冠脉病变程度的临床研究

目的:探讨运动后踝臂指数(ABI)与冠状动脉病变程度的相关性及对冠状动脉病变的预测价值。方法:选取2012年1月-2012年9月我院收治的冠心病行冠状动脉造影患者117例,根据造影结果分为正常组(38例)、轻中度病变组(45例)和严重病变组(34例),术前所有患者均行静息状态及运动后ABI检查。结果:轻中度病变组和重度病变组运动后ABI下降,各组间运动后ABI差异有显著性(P0.05)。由ROC曲线图可知,运动后ABI诊断冠心病及病变程度的准确性高于静息ABI诊断,差异具有统计学意义(P0.01)。结论:静息ABI和运动后ABI对冠心病均有诊断价值,运动后ABI诊断价值更高。静息下ABI和运动后ABI对冠状动脉严重病变有中等诊断价值,运动后ABI对冠状动脉严重病变诊断价值较高。

Application of Resting and Exercise Ankle-brachial Index on Evaluating the Severity of Coronary Artery Disease

Objective:To find the correlation between the extent of coronary lesions with ankle-brachial index (ABI) and the predictive value of coronary lesions of ABI and exercise ABI.Methods:117 patients who were suspected with coronary heart disease(CHD) were collected and divided into normal group and CHD group according to coronary arteriography results. The patients in the CHD group were further divided into mild-moderate lesions group and severe lesions group. The ABI and exercise ABI of patients were measured and compared. The ROC curve of ABI''s and exercise ABI''s diagnostic value were compared.Results:The exercise ABI between normal group and severe lesions group had significant difference. The exercise ABI in mild-moderate lesions group and ABI in severe lesions group were decreased. The excercise ABI''s AUC to diagnose serious coronary heart disease was better than ABI.Conclusion:Exercise ABI may have better predictive value of serious coronary lesions.