小儿幽门螺旋杆菌感染与缺铁性贫血的相关性分析

目的:分析并探讨小儿幽门螺杆菌感染与缺铁性贫血的相关性。方法:选择2012年2月至2013年2月本院门诊患儿412例,行血常规、血清铁、血清铁蛋白、HP-IgG抗体检测。结果:HP感染患儿IDA26例,IDA患病率为20.4%(26/127),HP未感染患儿IDA19例,IDA患病率为6.7%(19/285)。两者比较差异有统计学意义(x2=17.21,P=0.00)。对比两组患儿MCV、MCH、MCHC指标,差异具有显著性(P均0.05)。45例IDA患儿中26例有HP感染,感染率为57.8%(26/45),367例非IDA患儿中有101例HP感染,感染率为27.5%(101/367)。两者比较差异有统计学意义(x2=17.21,P=0.00)。结论:HP感染同IDA发病有显著相关性,HP感染可以是导致IDA的原因。

Correlation between Helicobacter Pylori Infection and Iron Deficiency Anemia in Children

Objective:To analyze and discuss the correlation of Helicobacter pylori infection and iron deficiency anemia of children.Methods:We choose 412 cases hospital outpatient children from February 2012 to February 2013, and test the blood count, serum iron, serum ferritin and HP-IgG antibodies.Results:26 HP infected children had IDA and the IDA prevalence was 20.4% (26/127), 19 HP-uninfected children had IDA, and the IDA HP prevalence was 6.7%(19/285). The difference was statistically significant (x2 = 17.21, P = 0.00). Compared the MCV, MCH, MCHC index of the two groups, the difference was significant (P<0.05). 26 out of 45 IDA children had HP infection, and the infection rate was 57.8% (26/45). 101 out of 367 children with non-IDA HP had infection, and the infection rate was 27.5% (101/367). The difference was statistically significant (x2= 17.21, P = 0.00).Conclusion:HP infection and the onset of IDA have significant correlation.HP infection may be the cause of IDA.