Species variations amongst proteinases in liver lysosomes |
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Authors: | Daniel Béchet Alain Obled Christiane Deval |
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Affiliation: | (1) S.R.V., Unité de Recherches sur les Protéines Musculaires, INRA Theix, 63122 Ceyrat, France |
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Abstract: | Cathepsin B, H, L and D activities in liver lysosomes were compared between species. Although cathepsin B and D were detected in bovine, pig, chicken and rat liver, striking species differences were evident for cathepsin H and L. Cathepsin L activity was particularly high in chicken lysosomal extracts, but could not be detected in bovine and pig extracts. Whereas there was no significant cathepsin H activity in bovine extracts, rat liver lysosomal extracts contained large amounts of cathepsin H activity. |
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Keywords: | species variation cystein proteinases cathepsin D liver lysosome |
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