Toxicity of organic solvents used in situ in microbial fermentation |
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| Authors: | Ján Marták Michal Rosenberg Štefan Schlosser L'udmila Krištofíková |
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| Affiliation: | (1) Department of Chemical and Biochemical Engineering, Slovak Technical University, Faculty of Chemical Technology, Radlinského 9, 812 37 Bratislava, Slovak Republic;(2) Department of Biochemical Technology, Slovak Technical University, Faculty of Chemical Technology, Radlinského 9, 812 37 Bratislava, Slovak Republic |
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| Abstract: | Summary Toxicity of organic solvents for in situ solvent extraction of carboxylic acids from aqueous solutions was studied on bacteria Bacillus subtillis and Acetobacter spp., yeasts Kluyveromyces marxianus and Pichia fermentans and fungi Aspergillus terreus and Rhizopus arrhizus. It has been found that trialkylamine and tributylphosphate are much more toxic than other carriers as trialkylphosphineoxide, triisobutylphosphinesulfide and trihexylphosphate. For R. arrhizus trihexylphosphate was found to be the less toxic solvent. |
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