Effect of high hydrostatic pressure on the porin OmpC from Escherichia coli |
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| Authors: | Macdonald A G Martinac B |
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| Affiliation: | Department of Biomedical Sciences, University of Aberdeen, UK. a.macdonald@abdn.ac.uk |
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| Abstract: | Porin OmpC from Escherichia coli was reconstituted in liposomes and its gating kinetics were recorded at high hydrostatic pressure, up to 90 MPa, using a development of the patch clamp technique. The composition of the recording solution influenced the results but generally high hydrostatic pressure favoured channel opening. |
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| Keywords: | Porin High hydrostatic pressure Channel gating |
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