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Alantolactone exhibits antiproliferative and apoptosis-promoting properties in colon cancer model via activation of the MAPK-JNK/c-Jun signaling pathway
Authors:Ren  Yijing  Lv  Cheng  Zhang  Jing  Zhang  Beibei  Yue  Bei  Luo  Xiaoping  Yu  Zhilun  Wang  Hao  Ren  Junyu  Wang  Zhengtao  Dou  Wei
Affiliation:1.The MOE key Laboratory of Standardization of Chinese Medicines, Shanghai Key Laboratory of Compound Chinese Medicines, and the SATCM key Laboratory of New Resources and Quality Evaluation of Chinese Medicines, Institute of Chinese Materia Medica, Shanghai University of Traditional Chinese Medicine (SHUTCM), Shanghai, 201203, China
;2.Key Laboratory of Cell Engineering in Guizhou Province, The Affiliated Hospital of Zunyi Medical University, Zunyi City, 563003, Guizhou Province, China
;
Abstract:Molecular and Cellular Biochemistry - Colorectal cancer (CRC) is one of the most common human malignancies in the digestive tract with high mortality. Alantolactone (ATL), as a plant-derived...
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