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Chemical Chaperone PBA Attenuates ER Stress and Upregulates SOCS3 Expression as a Regulator of Leptin Signaling |
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| Authors: | Baba Burcu Caliskan Mursel Boyuk Gulbahar Hacisevki Aysun |
| Affiliation: | 1.Department of Medical Biochemistry, Faculty of Medicine, Yuksek Ihtisas University, 06520, Ankara, Turkey ;2.Department of Genetic, Gaziosmanpa?a Hospital, Yeni Yuzyil University, 34245, Istanbul, Turkey ;3.Department of Physiology, Faculty of Medicine, Ankara Medipol University, 06050, Ankara, Turkey ;4.Department of Biochemistry, Faculty of Pharmacy, Gazi University, 06100, Ankara, Turkey ; |
| Abstract: | Biochemistry (Moscow) - Endoplasmic reticulum (ER) is very sensitive to the nutritional and energy states of the cells. Disruption of ER homeostasis leads to the accumulation of unfolded/misfolded... |
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