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Glutamine synthetase regulation by dexamethasone,RU486, and compound A in astrocytes derived from aged mouse cerebral hemispheres is mediated via glucocorticoid receptor
Authors:Kazazoglou  Theodosia  Panagiotou  Christina  Mihailidou  Chrysovalantou  Kokkinopoulou  Ioanna  Papadopoulou  Anna  Moutsatsou  Paraskevi
Institution:1.1st Department of Psychiatry, Eginition Hospital, Medical School, National and Kapodistrian University of Athens, Athens, Greece
;2.Cellular and Molecular Neurobiology Laboratory, University Mental Health, Neurosciences and Precision Medicine Research Institute “Costas Stefanis” (UMHRI), Athens, Greece
;3.Department of Clinical Biochemistry, Medical School, National and Kapodistrian University of Athens, University General Hospital “ATTIKON”, Rimini 1 str, Haidari, 12462, Athens, Greece
;4.Department of Biological Chemistry, Medical School, National and Kapodistrian University of Athens, Athens, Greece
;
Abstract:Molecular and Cellular Biochemistry - Glucocorticoids (GCs) regulate astrocyte function, while glutamine synthetase (GS), an enzyme highly expressed in astrocytes, is one of the most remarkable...
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