Combining Ribosomal Engineering with Heterologous Expression of a Regulatory Gene to Improve Milbemycin Production in Streptomyces milbemycinicus A2079 |
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Authors: | Wang S. Lu F. Yang Z. Li Z. Tian Y. |
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Affiliation: | 1.Key laboratory of Leather Chemistry and Engineering (Sichuan University), Ministry of Education, 610065, Chengdu, P. R. China ;2.College of Biomass Science and Engineering, Sichuan University, 610065, Chengdu, P. R. China ;3.Chengdu Jinkai Bioengineering Co., Ltd, 611130, Chengdu, P. R. China ; |
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Abstract: | Applied Biochemistry and Microbiology - Milbemycin, a group of 16-membered macrolide antibiotics produced by Streptomyces milbemycinicus, has been widely used as an insecticide and an anthelmintic.... |
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