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Leptin activates Akt in oesophageal cancer cells via multiple atorvastatin-sensitive small GTPases |
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| Authors: | Beales Ian L P Ogunwobi Olorunseun O |
| Institution: | 1.Department of Gastroenterology, Norfolk and Norwich University Hospital, Norwich, NR4 7UZ, UK ;2.Gastrioenterology Research Unit, Norwich Medical School, University of East Anglia, Norwich, NR4 7TJ, UK ; |
| Abstract: | Molecular and Cellular Biochemistry - Obesity is a risk factor for Barrett’s oesophagus and oesophageal adenocarcinoma. Adipose tissue secretes the hormone leptin. Leptin is a growth factor... |
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