| CRISPR-Cas系统在植物中的研究进展与监管政策 |
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| 作者姓名： | 刘肖静 王旭静 王志兴 |
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| 作者单位： | 中国农业科学院生物技术研究所, 农业农村部农业转基因生物安全评价（分子）重点实验室, 北京 100081 |
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| 基金项目： | 中央级公益性科研院所基本科研业务费项目。 |
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| 摘 要： | 基因编辑技术作为一种颠覆性新技术，现已广泛应用于作物的遗传改良，显示出巨大的发展潜力和应用价值。各国在加快技术研发的同时也十分关注其可能带来的安全性问题，相继出台了基因编辑作物的安全监管政策。综述了目前常用的CRISPR基因编辑系统的原理， 最新开发的一系列CRISPR变体，CRISPR系统在植物中的应用，基因编辑植物检测方法及国际上的相关监管政策，以期为我国基因编辑作物监管政策的制定提供理论数据。
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| 关 键 词： | CRISPR-Cas系统变体 CRISPR-Cas系统的应用 CRISPR-Cas系统的监管政策 |
| 收稿时间： | 2020-08-07 |
Research Advances and Regulation Policy of CRISPR-Cas System in Plants |
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| Authors: | LIU Xiaojing WANG Xujing WANG Zhixing |
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| Institution: | Key Laboratory on Safety Assessment (Molecular) of Agri-GMO, Ministry of Agriculture and Rural Affairs, Biotechnology Research Institute, Chinese Academy of Agricultural Sciences, Beijing 100081, China |
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| Abstract: | Gene editing technology,as a disruptive technology,has been widely used in crop genetic improvement,showing great development potential and application value.While increasing technology research and development,countries are also very concerned about the potential safety problems,and have introduced safety regulatory policies for gene editing crops.This paper mainly introduced the latest research progress of CRISPR system in plants(the mechanism of various newly developed variants of CRISPR,the application and challenges of CRISPR system),detection methods of gene editing plants and international regulatory policies.The paper was expected to provide theoretical data for the formulation of regulatory policies for gene editing crops in China. |
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| Keywords: | CRISPR-Cas system variant CRISPR-Cas system application CRISPR-Cas system regulatory policy |
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