Neurogenesis in the adult hippocampus |
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| Authors: | Dan Ehninger Gerd Kempermann |
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| Institution: | (1) Departments of Neurobiology, Psychology, and Psychiatry and the Brain Research Institute, University of California, Los Angeles, 695 Charles Young Drive South, Los Angeles, CA 90095–1761, USA;(2) Center for Regenerative Therapies Dresden, Am Tatzberg 47–49, 01307 Dresden, Germany |
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| Abstract: | New neurons continue to be generated in two privileged areas of the adult brain: the dentate gyrus of the hippocampal formation
and the olfactory bulb. Adult neurogenesis has been found in all mammals studied to date, including humans. The process of
adult neurogenesis encompasses the proliferation of resident neural stem and progenitor cells and their subsequent differentiation,
migration, and functional integration into the pre-existing circuitry. This article summarizes recent findings regarding the
developmental steps involved in adult hippocampal neurogenesis and the possible functional roles that new hippocampal neurons
might play. |
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| Keywords: | Neural stem cells Precursor cells Adult neurogenesis Hippocampus Learning and memory |
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