Silent generation of memory in genetic low-responder mice after a single contract with a bacterial antigen. |
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| Authors: | A J Macario E C de Macario |
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| Affiliation: | 1. Division of Biology and Medicine, Brown University, Providence, Rhode Island 02912 U.S.A.;2. Division of Laboratories and Research, New York State Department of Health, Albany, New York 12201 U.S.A. |
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| Abstract: | It is shown that immunologic memory can progressively develop following a single contact with a bacterial antigen (Escherichia coli β-d-galactosidase) in the absence of any sign of an antibody response. The relevance that this silent preparation for an anamnestic response might have in the pathogenesis of unexpected immune reactions is emphasized. |
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| Keywords: | Reprint requests: Division of Laboratories and Research New York State Department of Health Albany N.Y. 12201. |
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