X-ray enhances mating type switching in heterothallic strains of Saccharomyces cerevisiae |
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Authors: | Robert Schiestl and Ulrike Wintersberger |
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Affiliation: | (1) Institut für Krebsforschung der Universität Wien, Borschkegasse 8a, A-1090 Wien, Austria |
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Abstract: | Summary A procedure for the determination of the frequency of mating type switching in heterothallic strains of Saccharomyces cerevisiae was worked out. In cell populations irradiated with X-rays the frequencies of switching were enhanced in a dose-dependent manner. The possible implication of this finding for understanding the mechanism of carcinogenesis is discussed. |
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