Plasmid and chromosome segregation in prokaryotes |
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| Authors: | Møller-Jensen J Jensen R B Gerdes K |
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| Affiliation: | Dept of Biochemistry and Molecular Biology, SDU-Odense University, Campusvej 55, DK-5230 Odense M, Denmark. |
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| Abstract: | Recent major advances in the understanding of prokaryotic DNA segregation have been achieved by using fluorescence microscopy to visualize the localization of cellular components. Plasmids and bacterial chromosomes are partitioned in a highly dynamic fashion, suggesting the presence of a mitotic-like apparatus in prokaryotes. The identification of chromosomal homologues of the well-characterized plasmid partitioning genes indicates that there could be a general mechanism of bacterial DNA partitioning. |
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