光诱导角膜交联及检测技术的研究进展

由于圆锥角膜疾病导致越来越多的人患有近视,常见的矫正方法有佩戴近视眼镜、隐形眼镜等.随着科技的进步,利用光对近视等眼科疾病进行屈光矫正已经成为当前临床中常用的方法.使用光诱导角膜胶原蛋白发生交联,从而达到治疗圆锥角膜疾病、提高患者视力水平的目的,这是一种新型的光治疗眼睛疾病的方法.同时这种方法由于无侵入性、对操作者能力依赖性小等优势成为新的研究热点.本文阐述光诱导角膜交联的基本原理,并介绍其发展历程,分析现有的各种交联方法和角膜检测技术的原理,并对现有交联方法和检测方法的优缺点进行讨论.最后,本文对光诱导角膜交联和检测技术的最新进展进行系统的论述,并对未来的发展趋势进行展望.

Research progress of light induced corneal cross-linking and its detection technology

More and more people suffer from myopia due to keratoconus disease. Common correction methods include wearing myopia glasses, contact lenses, etc. With the progress of science and technology, the use of light for refractive correction of myopia and other ophthalmic diseases has become a common clinical method. The light can induce the cross-linking of corneal collagen, so as to treat keratoconus disease and improve the visual acuity of patients. At the same time, this method has become a novel research focus due to its merits of non-invasive and low dependence on operator ability. In this paper, the basic principle and development of light-induced corneal crosslinking are introduced, meanwhile the principles of various existing cross-linking methods and corneal detection techniques are analyzed, and the advantages and disadvantages of the existing cross-linking methods and detection methods are discussed. Finally, the latest development of light-induced corneal crosslinking and detection technology is systematically discussed, and prospected the future development trend of light-induced corneal crosslinking and detection technology.