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基于主成分分析的随机森林视网膜OCT图像分层算法研究
引用本文:李晓雯,王陆权,曾亚光,陈允照,王茗祎,钟俊平,王雪花,熊红莲,陈勇.基于主成分分析的随机森林视网膜OCT图像分层算法研究[J].生物化学与生物物理进展,2021,48(3):336-343.
作者姓名:李晓雯  王陆权  曾亚光  陈允照  王茗祎  钟俊平  王雪花  熊红莲  陈勇
作者单位:1)佛山科学技术学院自动化学院,佛山 528000,1)佛山科学技术学院自动化学院,佛山 528000,2)佛山科学技术学院物理与光电工程学院,佛山 528000,2)佛山科学技术学院物理与光电工程学院,佛山 528000,2)佛山科学技术学院物理与光电工程学院,佛山 528000,2)佛山科学技术学院物理与光电工程学院,佛山 528000,2)佛山科学技术学院物理与光电工程学院,佛山 528000,2)佛山科学技术学院物理与光电工程学院,佛山 528000,1)佛山科学技术学院自动化学院,佛山 528000
基金项目:国家自然科学基金(81601534, 61771139, 61805038, 61705036)、国家重点研发计划(2018YFC1406601)和广东省自然科学基金(2017A030313386)资助项目.
摘    要:视网膜是层状结构,临床上可以根据视网膜层厚度改变对一些疾病进行预测和诊断.为了快速且准确地分割出视网膜的不同层带,本论文提出一种基于主成分分析的随机森林视网膜光学相干断层扫描技术(optical coherence tomography,OCT)图像分层算法.该方法使用主成分分析(principal component analysis,PCA)法对随机森林采集到的特征进行重采样,保留重采样后权重大的特征信息维度,从而消除特征维度间的关联性和信息冗余.结果表明,总特征维度在29维的情况下,保留前18维度训练速度提高了23.20%,14维度训练速度提高了42.38%,而对图像分割精度方面影响较小,实验表明该方法有效地提高了算法的效率.

关 键 词:光学相干断层扫描技术(OCT)  视网膜分层  主成分分析  随机森林
收稿时间:2020/7/29 0:00:00
修稿时间:2020/8/21 0:00:00

Random Forest Retinal Segmentation in OCT Images Based on Principal Component Analysis
LI Xiao-Wen,WANG Lu-Quan,ZENG Ya-Guang,CHEN Yun-Zhao,WANG Ming-Yi,ZHONG Jun-Ping,WANG Xue-Hu,XIONG Hong-Lian and CHEN Yong.Random Forest Retinal Segmentation in OCT Images Based on Principal Component Analysis[J].Progress In Biochemistry and Biophysics,2021,48(3):336-343.
Authors:LI Xiao-Wen  WANG Lu-Quan  ZENG Ya-Guang  CHEN Yun-Zhao  WANG Ming-Yi  ZHONG Jun-Ping  WANG Xue-Hu  XIONG Hong-Lian and CHEN Yong
Institution:1)Automatic College, Foshan University, Foshan 528000, China,1)Automatic College, Foshan University, Foshan 528000, China,2)School of Physics and Optoelectronic Engineering, Foshan University, Foshan 528000, China,2)School of Physics and Optoelectronic Engineering, Foshan University, Foshan 528000, China,2)School of Physics and Optoelectronic Engineering, Foshan University, Foshan 528000, China,2)School of Physics and Optoelectronic Engineering, Foshan University, Foshan 528000, China,2)School of Physics and Optoelectronic Engineering, Foshan University, Foshan 528000, China,2)School of Physics and Optoelectronic Engineering, Foshan University, Foshan 528000, China,1)Automatic College, Foshan University, Foshan 528000, China
Abstract:The retina is a layered structure, and some diseases can be clinically predicted and diagnosed based on the change in the thickness of the retinal layer. To segment the different layers of the retina quickly and accurately, this study proposes a random forest algorithm based on principal component analysis (PCA). The algorithm uses PCA to resample the normalized features collected from the retinal images and retains the feature information dimensions with significant weight, thereby eliminating the relevance between the different feature dimensions and information redundancy. After PCA, the number of features can be reduced obviously, but still retains 99% information. Random forests algorithm applies the features to learn and predict the location of retinal layer boundaries. We extract each pixels values of retinal boundaries, producing an accurate probability map for each boundary. Experimental results show that when the total number of feature dimensions decreased from 29 to 18, the training speed of the model increased by 23.20%. By contrast, when the number of feature dimensions was 14, the training speed increased by 42.38%. However, the effect on image segmentation accuracy was not obvious. Thus, it is found that this method effectively improves the efficiency of the algorithm.
Keywords:optical coherence tomography (OCT)  retina segment  principal component analysis (PCA)  random forest (RF)
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