Genomic position mapping discrepancies of commercial SNP chips |
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| Authors: | Fadista João Bendixen Christian |
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| Affiliation: | 1. Department of Clinical Sciences Malmö, CRC, Lund University, Malmö, Sweden.; 2. Department of Molecular Biology and Genetics, Faculty of Science and Technology, Aarhus University, Tjele, Denmark.;Emory University School Of Medicine, United States of America |
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| Abstract: | The field of genetics has come to rely heavily on commercial genotyping arrays and accompanying annotations for insights into genotype-phenotype associations. However, in order to avoid errors and false leads, it is imperative that the annotation of SNP chromosomal positions is accurate and unambiguous. We report on genomic positional discrepancies of various SNP chips for human, cattle and mouse species, and discuss their causes and consequences. |
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