| Abstract: | Biohybrid implalts represent a new class of medical device in which living cells, supported in a hydrogel matrix, and surrounded by semipepmiable membrane, produce and deliver therapeutic reagents tm specific sites wthin a host. First prpmsed in the mid-1970s for tpeatment modality has progressed rapidly in the past four years and is now being investigated not just for endcrine disorders but also for alleviation of chronic pain, treatment of neurodegenerative disorders, and delivery of neurotrophic factors to sites withil the blood brain barrier, and aq a practical alternative to conventional ex vivo. |
