Cytogenetic investigation of occupational exposure to epichlorohydrin |
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| Affiliation: | 1. “Gh. Asachi” Technical University Iasi, Department: Textiles, Leather and Industrial Management, 29 Mangeron Street, Iasi 20050, Romania;2. “Gr.T. Popa” University of Medicine and Pharmacy, Faculty of Pharmacy/Department of Pharmaceutical Technology, 11 Universitatii Street, Iasi, Romania;1. School of Mechanical & Automotive Engineering, Qilu University of technology (Shandong Academy of Sciences), Jinan 250353, PR China;2. School of Mechanical Engineering, Shandong University of Technology, Zibo 255000, PR China |
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| Abstract: | Cytogenetic evaluation of peripheral lymphocytes from 93 workers currently exposed to epichlorohydrin has revealed an increase in aberration rates as compared to that of a 75-person group seen for preemployment examination. Statistically significant differences were found in the distribution of individuals with chromatid breaks, chromosome breaks, severely damaged cells, and total abnormal cells. These results confirm the observations of Kucerova et al. in a similar occupational group. |
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