Mutagenicity of aliphatic nitrosamines in Salmonella typhimurium |
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| Affiliation: | 1. Laboratory of Cardiac Biophysics, Instituto de Fisiología and Facultad de Medicina, Universidad Autónoma de Puebla, Puebla, Mexico |
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| Abstract: | 25 aliphatic nitrosamines were examined in the Ames assay for bacterial mutagens, using rat liver “S-9” for activation. Of them, 8 carcinogens were mutagenic and 5 non-carcinogens were not mutagenic. However, 2 compounds not carcinogenic in rats were mutagenic and 9 carcinogens were not mutagenic, including 6 that are liver carcinogens in rats. |
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