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Conditioned place avoidance is associated with a distinct hippocampal phenotype,partly preserved pattern separation,and reduced reactive oxygen species production after stress |
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| Authors: | D Parker Kelley Lucas Albrechet-Souza Shealan Cruise Rajani Maiya Aspasia Destouni Siva S V P Sakamuri Alexander Duplooy Meghan Hibicke Charles Nichols Prasad V G Katakam Nicholas W Gilpin Joseph Francis |
| Institution: | 1. Comparative Biomedical Sciences, Louisiana State University School of Veterinary Medicine, Baton Rouge, Louisiana, USA;2. Department of Cell Biology & Anatomy, Louisiana State University Health Sciences Center, New Orleans, Louisiana, USA;3. Department of Physiology, Louisiana State University Health Sciences Center, New Orleans, Louisiana, USA;4. Department of Pharmacology, Tulane University School of Medicine, New Orleans, Louisiana, USA;5. Department of Pharmacology and Experimental Therapeutics, Louisiana State University Health Sciences Center, New Orleans, Louisiana, USA;6. Alcohol & Drug Abuse Center of Excellence, Louisiana State University Health Sciences Center, New Orleans, Louisiana, USA |
| Abstract: | |
| Keywords: | conditioned place avoidance (CPA) dentate gyrus DG-CA3 differentially expressed genes (DEGs) dorsal hippocampus electron paramagnetic resonance spectroscopy (EPR) electron spin resonance spectroscopy (ESR) hippocampus (HPC) maximal respiratory capacity metabolism mitochondria mitochondrial spare respiratory capacity object pattern separation (OPS) oxygen consumption rate (OCR) predator odor reactive oxygen species (ROS) RNA sequencing (RNAseq) seahorse extracellular flux analysis (SEFA) stress weighted genome correlational network analysis (WGCNA) |