| 反义肽及其在生化分离中的应用 |
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| 引用本文： | 林启山,刘国诠. 反义肽及其在生化分离中的应用[J]. 生物化学与生物物理进展, 1995, 22(5): 415-419 |
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| 作者姓名： | 林启山 刘国诠 |
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| 作者单位： | 中国科学院化学研究所;中国科学院化学研究所 |
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| 摘 要： | 反义肽是由反义RNA编码和翻译的肽．它可与其正义肽分子发生专一性相互作用．近年反义肽的这种特异性结合实例研究，已为其在生化分离领域应用奠定了基础，尤其是在色谱亲和配基的选择方面，可以预见不久以反义肽为配基的亲和色谱将是生物工程产品分离的一种有效手段．
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| 关 键 词： | 反义肽 专一性相互作用 亲和色谱 |
| 收稿时间： | 1994-09-26 |
| 修稿时间： | 1995-01-19 |
Antisense Peptide and Its Application in the Separation of Bioproducts |
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| Lin Qishan and Liu Guoquan. Antisense Peptide and Its Application in the Separation of Bioproducts[J]. Progress In Biochemistry and Biophysics, 1995, 22(5): 415-419 |
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| Authors: | Lin Qishan and Liu Guoquan |
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| Affiliation: | Institute of Chemistry, Academia Sinica;Institute of Chemistry, Academia Sinica |
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| Abstract: | Antisense peptides encoded in the antisense strand of DNA can bind to sense peptides and proteins with significant affinity and selectivity. Sense-antisense peptide recognition observed in many systems lays a foundation in the separation of bioproducts especially in the selection of chromatographic affinity ligand.Affinity chromatography immobilized with antisense peptides will be a best alternative choice for separation of biotechnical products. |
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| Keywords: | antisense peptide specificity interaction affinity chromatograp |
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