Satellite DNA and disease--possible mechanisms. Minisatellite instability |
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Authors: | Patkin E L Gaĭtskhoki V S |
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Affiliation: | Institute of Experimental Medicine, Russian Academy of Sciences, St. Petersburg, Russia. |
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Abstract: | The main possible molecular mechanisms of minisatellite DNA instability are reviewed and compared with those of the trinucleotide repeat instability. Evidence indicating that some human diseases are associated with minisatellite DNA instability is presented including data on minisatellite DNA expansion. |
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