Syntheses and advanced NMR structure determination of androsteno-[17,16-d]-pyrimidine derivatives |
| |
Authors: | Forgo Peter Vincze Irén |
| |
Institution: | Department of Organic Chemistry, University of Szeged, Dóm tér 8, H-6720, Szeged, Hungary. pforgo@chem.u-szeged.hu |
| |
Abstract: | Reactions of 16-hydroxymethylene- and 16-aminomethylene-3beta-hydroxy-5-androsten-17-one with formamide and guanidine were carried out resulting in the formation of 16,17-d]-pyrimidine rings. Advanced two-dimensional NMR methods were used to investigate the structure of the products. Homonuclear-, and heteronuclear chemical shift correlation experiments yielded the complete 1H-, 13C- and 15N signal assignment for these compounds. |
| |
Keywords: | |
本文献已被 PubMed 等数据库收录! |
|