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A comprehensive nomenclature for serine proteases with homology to tissue kallikreins |
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| Authors: | Lundwall Ake Band Vimla Blaber Michael Clements Judith A Courty Yves Diamandis Eleftherios P Fritz Hans Lilja Hans Malm Johan Maltais Lois J Olsson A Yvonne Petraki Constantina Scorilas Andreas Sotiropoulou Georgia Stenman Ulf-Håkan Stephan Carsten Talieri Maroulio Yousef George M |
| Affiliation: | Lund University, Clinical Chemistry, Department of Laboratory Medicine, University Hospital MAS, S-205 02 Malm?, Sweden. ake.lundwall@med.lu.se |
| Abstract: | The human kallikrein locus on chromosome 19q13.3-13.4 contains kallikrein 1--the tissue kallikrein--and 14 related serine proteases. Recent investigations into their function and evolution have indicated that the present nomenclature for these proteins is inadequate or insufficient. Here we present a new nomenclature in which proteins without proven kininogenase activity are denoted kallikrein-related peptidase. Names are also given to the unique rodent proteins that are closely related to kallikrein 1. |
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