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Orosomucoid (ORM) typing by isoelectric focusing: evidence for two structural loci ORM1 and ORM2
Authors:I. Yuasa  K. Umetsu  K. Suenaga  M. Robinet-Levy
Affiliation:(1) Department of Legal Medicine, Tottori University School of Medicine, 683 Yonago, Japan;(2) Department of Forensic Medicine, Yamagata University School of Medicine, 990-23 Yamagata, Japan;(3) Yamaguchi Red Cross Hospital, 753 Yamaguchi, Japan;(4) Centre de Transfusion Sanguine, Institut d'Hematologie, F-34010 Montpellier, France
Abstract:Summary Orosomucoid (ORM) phenotyping was performed by isoelectric focusing and immunoprinting. The band patterns of desialyzed ORM indicated that the ORM system is controlled by two structural loci ORM1 and ORM2. In a total of 253 samples from two Caucasoid populations, five phenotypes determined by three polymorphic alleles, ORM1*1, ORM1*2, and ORM1*3 were identified. The ORM1*3 was characteristic of the Caucasoids. The ORM2 locus was monomorphic.
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