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Disruption of peroxisome proliferator-activated receptor α in hepatocytes protects against acetaminophen-induced liver injury by activating the IL-6/STAT3 pathway |
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| Authors: | Zhenzhen Zhang Tiantian Yao Nan Zhao Hui Liu Hao Cheng Frank J Gonzalez Hua Wang Guiqiang Wang Aijuan Qu Yan Wang |
| Abstract: | |
| Keywords: | Acetaminophen (APAP), Hepatotoxicity, Peroxisome proliferator-activated receptor α (PPARα ), Oxidative stress, IL-6/STAT3, Liver injury, Liver repair |