| 蛋白质编码区与非编码区的特征与识别 |
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| 引用本文： | 孟捷,陈滔.蛋白质编码区与非编码区的特征与识别[J].生物数学学报,1996,11(2):75-82. |
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| 作者姓名： | 孟捷 陈滔 |
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| 作者单位： | 中国科学院昆明动物研究所细胞与分子进化开放实验室，云南大学非线性（复杂）系统联合实验室!昆明650223 |
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| 基金项目： | 中国科学院昆明动物研究所细胞与分子进化开放实验室资助 |
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| 摘 要： | 在核苷酸序列分析中，一个重要的问题是如何识别一段未知序列中的编码区和非编码区．近年来提出了一些方法，但效果都不够理想．本文在对编码区与非编码区特征进行大量统计分析的基础上，提出一种加权距离判别法，并对该方法的精度进行了评价．
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| 关 键 词： | 三核苷酸与四核苷酸频数分布 编码区 非编码区 加权距离判别 |
THE CHARACTER AND IDENTIFYING OF PROTEIN CODING AND NON-CODING REGION |
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| Meng Jie,Chen Tao,Liu Ciquan,Peng Shouli,Hu Guangtao,Yang Zhitian,Zhang Xusheng,Chen Zhongxuan,Chen Lin,Wang Yunxiang,Zheng Jian,and Zhang Jin.THE CHARACTER AND IDENTIFYING OF PROTEIN CODING AND NON-CODING REGION[J].Journal of Biomathematics,1996,11(2):75-82. |
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| Authors: | Meng Jie Chen Tao Liu Ciquan Peng Shouli Hu Guangtao Yang Zhitian Zhang Xusheng Chen Zhongxuan Chen Lin Wang Yunxiang Zheng Jian and Zhang Jin |
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| Institution: | Meng Jie;Chen Tao;Liu Ciquan;Peng Shouli;Hu Guangtao;Yang Zhitian;Zhang Xusheng;Chen Zhongxuan;Chen Lin;Wang Yunxiang;Zheng Jian;and Zhang Jin(Laboratory of cellular and Molecular Evolution Kunming Institute of Zoology Academia Sinica Kunming 650223 |
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| Abstract: | How to discriminate between protein coding and non-coding is very important in analysis of nucleotide sequences.Several methods were suggested,but these methods are not very effective.In this paper,a weighted distance discrimination was suggested based on statistical analysis of protein coding and non-coding regions.Evaluation of this method was also provided. |
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| Keywords: | Weighted distance discrimination coding non-coding frequency of triplet and quadruplet |
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