Synthesis and biological evaluation of novel isoxazolo[4,3-e]indoles as antibacterial agents |
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| Authors: | Mehdi Pordel Amin Abdollahi Bahareh Razavi |
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| Affiliation: | 16462. Department of Chemistry, Mashhad Branch, Islamic Azad University, Mashhad, Iran
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| Abstract: | The synthesis of a new series of 8-bromo-6-alkyl-1-aryl-6H-isoxazolo[4,3-e]indole derivatives is described. All the newly synthesized compounds were screened for their antibacterial activity against Escherichia coli HB101, Staphylococcus aureus pathogens (methicillin resistant S. aureus and methicillin susceptible S. aureus), Pseudomonas aeruginosa, and Bacillus subtilis; also MIC values of these compounds were determined. |
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