| 以肠道菌群为靶向的粪菌移植法及其在畜牧业的应用潜能 |
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| 引用本文： | 李晓蕾,李地艳,孙静. 以肠道菌群为靶向的粪菌移植法及其在畜牧业的应用潜能[J]. 中国实验动物学报, 2019, 0(1): 124-128 |
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| 作者姓名： | 李晓蕾 李地艳 孙静 |
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| 作者单位： | 重庆市畜牧科学院农业部养猪科学重点实验室;四川农业大学动物遗传育种研究所;重庆市养猪科学重点实验室;重庆市医用动物资源开发与利用工程技术研究中心 |
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| 基金项目： | 重庆市农发资金项目(17408);重庆市基本科研业务费项目(16422);重庆市博士后科研项目特别资助项目(Xm2016031)~~ |
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| 摘 要： | 肠道微生物与宿主机体健康息息相关。粪便微生物移植(又称为粪菌移植,fecal microbiota transplantation,FMT)通过将健康供体粪便中的完整肠道菌群移入肠道微生态失衡的患者胃肠道内,经肠道菌群重构、恢复至正常状态。用FMT治疗某些肠道疾病如复发性艰难梭菌感染、溃疡性结肠炎、肠易激综合症、克罗恩病效果显著,且可能对因肠道菌群紊乱引起的肠道外疾病的治疗有潜在价值。本文主要对FMT技术的发展进程、在疾病上的研究以及在畜牧业上的应用潜能进行综述,并分析其应用的制约因素。
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| 关 键 词： | 粪便微生物移植 肠道菌群平衡 畜牧业 |
Intestinal flora-targeted fecal microbiota transplantation and its potential applications in animal husbandry |
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| LI Xiaolei,LI Diyan,SUN Jing. Intestinal flora-targeted fecal microbiota transplantation and its potential applications in animal husbandry[J]. Acta Laboratorium Animalis Scientia Sinica, 2019, 0(1): 124-128 |
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| Authors: | LI Xiaolei LI Diyan SUN Jing |
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| Affiliation: | (Key Laboratory of Pig Industry Science, Ministry of Agriculture, Chongqing 402460, China;Chongqing Key Laboratory of PigIndustry Sciences, Chongqing 402460, China;Technical Engineering Center for the Development and Utilization of Medical AnimalResources, Chongqing Academy of Animal Science, Chongqing 402460, China;Institute of AnimalGenetics and Breeding, Sichuan Agricultural University, Chengdu 611130,China) |
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| Abstract: | LI Xiaolei;LI Diyan;SUN Jing(Key Laboratory of Pig Industry Science, Ministry of Agriculture, Chongqing 402460, China;Chongqing Key Laboratory of PigIndustry Sciences, Chongqing 402460, China;Technical Engineering Center for the Development and Utilization of Medical AnimalResources, Chongqing Academy of Animal Science, Chongqing 402460, China;Institute of AnimalGenetics and Breeding, Sichuan Agricultural University, Chengdu 611130,China) |
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| Keywords: | fecal microbiota transplantation gut microbial balance animal husbandry |
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