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The proteomes of the human eye,a highly compartmentalized organ
Authors:Gilbert S. Omenn
Affiliation:Center for Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI, USA
Abstract:Proteomics has now published a series of Dataset Briefs on the EyeOme from the HUPO Human Proteome Project with high‐quality analyses of the proteomes of these compartments of the human eye: retina, iris, ciliary body, retinal pigment epithelium/choroid, retrobulbar optic nerve, and sclera, with 3436, 2929, 2867, 2755, 2711, and 1945 proteins, respectively. These proteomics resources represent a useful starting point for a broad range of research aimed at developing preventive and therapeutic interventions for the various causes of blindness.
Keywords:Biomedicine  Biology and Disease‐driven Human Proteome Project  End Blindness by 2020  Eye proteome  EyeOme  Human Proteome Project
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