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Substantial Metabolic Activity of Human Brown Adipose Tissue during Warm Conditions and Cold-Induced Lipolysis of Local Triglycerides
Authors:Graeme Weir  Lynne E. Ramage  Murat Akyol  Jonathan K. Rhodes  Catriona J. Kyle  Alison M. Fletcher  Thomas H. Craven  Sonia J. Wakelin  Amanda J. Drake  Maria-Lena Gregoriades  Ceri Ashton  Nick Weir  Edwin J.R. van Beek  Fredrik Karpe  Brian R. Walker  Roland H. Stimson
Affiliation:1. BHF/University Centre for Cardiovascular Science, University of Edinburgh, The Queen’s Medical Research Institute, 47 Little France Crescent, Edinburgh EH16 4TJ, Scotland, UK;2. Department of Radiology, Royal Infirmary of Edinburgh, Edinburgh, Scotland, UK;3. Department of Surgery, Royal Infirmary of Edinburgh, Edinburgh, Scotland, UK;4. Department of Anaesthesia and Critical Care, University of Edinburgh, Edinburgh, Scotland, UK;5. Edinburgh Imaging Facility QMRI, University of Edinburgh, Edinburgh, Scotland, UK;6. Department of Radiology, Western General Hospital, Edinburgh, Scotland, UK;7. Department of Medical Physics, Royal Infirmary of Edinburgh, Edinburgh, Scotland, UK;8. Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, UK;9. NIHR Oxford Biomedical Research Centre, OUH Trust, Oxford, UK;10. Institute of Genetic Medicine, Newcastle University, Newcastle upon Tyne, UK
Abstract:
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  • Keywords:brown adipose tissue  cold exposure  human  PET/CT  microdialysis  tracer  substrate utilization  physiology
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