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An MRI-Compatible High Frequency AC Resistive Heating System for Homeothermic Maintenance in Small Animals
Authors:Stuart Gilchrist  Ana L. Gomes  Paul Kinchesh  Veerle Kersemans  Philip D. Allen  Sean C. Smart
Affiliation:Cancer Research UK and Medical Research Council Oxford Institute for Radiation Oncology, Department of Oncology, University of Oxford, Oxford, United Kingdom;University of Glasgow, UNITED KINGDOM
Abstract:PurposeTo develop an MRI-compatible resistive heater, using high frequency alternating current (AC), for temperature maintenance of anaesthetised animals.ResultsImages and spectra acquired in the presence and absence of 50–100 kHz AC through the wire heater were indistinguishable, whereas DC power created field shifts and lineshape distortions. Temperature lost during induction of anaesthesia was recovered within approximately 20 minutes and a stable temperature was reached as the mouse’s temperature approached the set target.ConclusionThe AC-powered wire heater maintains adequate heat input to the animal to maintain body temperature, and does not compromise image quality.
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