Harmful algal bloom causative collected from Hong Kong waters |
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| Authors: | Lu Songhui Hodgkiss I.J. |
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| Affiliation: | 1. Department of Biotechnology, Malankara Catholic College, Mariagiri, Kaliakavilai –, 629153, Kanyakumari District, India
2. Marine Biotechnology Laboratory, Central Marine Fisheries Research Institute, Vizhinjam –, 695 521, Thiruvananthapuram, India
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| Abstract: | The secondary metabolites of three sponges collected as bycatch in the fishing nets were explored for biological potencies. The sponge Dendrilla nigraexhibited wider biological activity. It showed potent activity in antibacterial, brineshrimp cytotoxicity, larvicidal, antifouling and ichthyotoxic assays. One of the well-studied cytotoxic sponge Axinella donnaniwas least active in brineshrimp cytotoxicity assay. The secondary metabolites of Clathria gorgonoideswere highly cytotoxic albeit it showed least activity in other bioassays. Based on the present findings, it could be inferred that the bioassay-guided fractionation and purification of D. nigramay come up with potent bioactive drugs. % |
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