Analysing the origin of long-range interactions in proteins using lattice models |
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| Authors: | Orly Noivirt-Brik Ron Unger Amnon Horovitz |
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| Affiliation: | (1) Department of Structural Biology, Weizmann Institute of Science, Rehovot, 76100, Israel;(2) The Mina & Everard Goodman Faculty of Life Sciences, Bar-Ilan University, Ramat-Gan, 52900, Israel |
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| Abstract: | Background Long-range communication is very common in proteins but the physical basis of this phenomenon remains unclear. In order to gain insight into this problem, we decided to explore whether long-range interactions exist in lattice models of proteins. Lattice models of proteins have proven to capture some of the basic properties of real proteins and, thus, can be used for elucidating general principles of protein stability and folding. |
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