The use of RNA interference for the metabolic engineering of plants (Review) |
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Authors: | E B Rukavtsova V V Alekseeva Ya I Buryanov |
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Institution: | (1) Division of Cancer Biology and Angiogenesis, Department of Pathology, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts, USA |
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Abstract: | The metabolic engineering of plants is aimed at the realization of new biochemical reactions by transgenic cells. These reactions
are determined by enzymes encoded by foreign or self-modified genes. Plants are considered to be the most interesting objects
for metabolic engineering. Although they are characterized by the same pathways for the synthesis of basic biological compounds,
plants differ by the astonishing diversity of their products: sugars, aromatic compounds, fatty acids, steroid compounds,
and other biologically active substances. RNA interference aimed at modifying metabolic pathways is a powerful tool that allows
for the obtainment of plants with new valuable properties. The present review discusses the main tendencies for research development
directed toward the obtainment of transgenic plants with altered metabolism. |
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