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2,6-Quinolinyl derivatives as potent VLA-4 antagonists |
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| Authors: | Lassoie Marie-Agnès Broeders Fabienne Collart Philippe Defrère Laurent de Laveleye-Defais Françoise Demaude Thierry Gassama Abdoulaye Guillaumet Gérald Hayez Jean-Claude Kiss Laszlo Knerr Laurent Nicolas Jean-Marie Norsikian Stéphanie Quéré Luc Routier Sylvain Verbois Valérie Provins Laurent |
| Affiliation: | UCB S.A., R&D, Chemin du Foriest, B-1420 Braine-l'Alleud, Belgium. |
| Abstract: | A new series of 2,6-quinolinyl derivatives was prepared leading to potent low nanomolar VLA-4/VCAM-1 antagonists. |
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