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Metformin-induced inhibition of the mitochondrial respiratory chain increases FGF21 expression via ATF4 activation |
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| Authors: | Kook Hwan Kim Yeon Taek Jeong Seong Hun Kim Hye Seung Jung Kyong Soo Park Hae-Youn Lee Myung-Shik Lee |
| Institution: | 1. Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, 50 Irwon-dong Gangnam-gu, Seoul 135-710, South Korea;2. Samsung Advanced Institute for Health Sciences and Technology, Sungkyunkwan University School of Medicine, 50 Irwon-dong Gangnam-gu, Seoul 135-710, South Korea;3. Department of Internal Medicine, Seoul National University College of Medicine, 28 Yongon-dong Chongno-gu, Seoul 110-744, South Korea |
| Abstract: | |
| Keywords: | Metformin FGF21 ATF4 AMPK Diabetes |
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