A hepatic membrane-associated factor stimulates nuclear DNA synthesis in cultured fibroblastic cells |
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| Authors: | Subal Bishayee Manjusri Das |
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| Affiliation: | Department of Biochemistry and Biophysics, University of Pennsylvania School of Medicine, Philadelphia, PA 19104 U.S.A. |
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| Abstract: | Nuclear DNA replication in cultured mouse fibroblasts is stimulated by isolated hepatic plasma membranes in a time- and concentration-dependent manner. The plasmalemmal activity is susceptible to trypsin treatment, and to treatment with protein modifying agents, N-ethylmaleimide, N-bromosuccinimide, and 2-hydroxy-5-nitro-benzylbromide. |
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| Keywords: | Plasma membrane Growth factor Nuclear DNA synthesis (Mouse liver) |
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