肝门部胆管癌临床诊断与放疗疗效分析 |
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引用本文: | 周海华,杨倞,孙永健,孟岩,霍爽. 肝门部胆管癌临床诊断与放疗疗效分析[J]. 生物磁学, 2014, 0(9): 1665-1667 |
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作者姓名: | 周海华 杨倞 孙永健 孟岩 霍爽 |
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作者单位: | [1]第二军医大学附属东方肝胆外科医院放疗中心,上海200438 [2]哈尔滨医科大学,黑龙江哈尔滨150081 |
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基金项目: | 基金项目:国家自然科学基金项目(81170397) |
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摘 要: | 目的:探讨不同手术方式治疗肝门部胆管癌的效果及其对术后放疗的影响。方法:回顾性分析我科自2008年6月至2012年6月间收治的60例肝门部胆管癌患者的临床资料,根据手术方式不同,将所选病例分为两组,其中26例接受根治性切除术,34例患者采用姑息性手术进行治疗。对比不同手术方式下放疗后患者生存情况。结果:围手术期死亡1例。两组患者各有2例患者失访。随访的23例根治手术患者1、3、5年间的生存率为19(82.6%)、10(43.5%)、2(8.7%);32例姑息性手术患者1、3、5年间的生存率为15(46.9%)、4(12.4%)、0(0%)。根治性手术后患者1、3、5年间的生存率显著性高于姑息性手术治疗的患者,差异具有统计学意义(P〈0.05)。结论:通过术前影像学诊断,选择合理的手术方式,联合术后放疗,可有效延长肝门部胆管癌患者的生存时间。
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关 键 词: | 胆管肿瘤 根治性手术 姑息治疗 放射治疗 临床效果 |
Diagnosis and Effects of the Radiotherapy on Hilar Cholangiocarcinoma |
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Affiliation: | ZHOU Hai-hua, YANG Lian, SUN Yong-jian, MENG Yan, HUO Shuan (1 Department of Radiation, Eastern Hepatobiliary Surgery Hospital, aftfliated to the Second Military Medical Universi(y, Shanghai, 2 Harbin Medical Universi(y, Harbin, Heilong/iang, 150081, China) |
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Abstract: | Objective: To investigate the clinical effects of different operation methods combined with the radiotherapy on the treatment of hilar cholangiocarcinoma. Methods: A retrospective analysis was conducted about 60 cases with hilar cholangiocarcinoma who were treated in our hospital from June 2008 to June 2012. Results: The rate of misdiagnosis was high without specific symptoms in the early stage. There was one died when undergoing the radical surgery, and two cases were missed the follow-up in each group. The median survival time of 23 patients treated by radical resection was 30 months with the 1, 3, 5-year survival rate 19(82.6%), 0(43.5%), 2 (8.7%) respectively. While the median survival time of the non-radical 32 patients was 16 months with the 1, 3, 5-year survival rate 15 (46.9%), 4 (12.4%), 0 (0%) respectively. Conclusions: It is indicated that a reasonable surgical approach combined with postoperative radiotherapy should be performed by the preoperative imaging diagnosis in order to effectively extend the hilar survival time of patients. |
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Keywords: | Bileduct neoplasms (Non)radical surgery Clinical diagnosis Treat analysis |
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