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Proteomics Reveals Multiple Phenotypes Associated with N-linked Glycosylation in Campylobacter jejuni
Affiliation:3. From the 3School of Life and Environmental Sciences,;4. 4Charles Perkins Centre,;5. 5Discipline of Pathology, School of Medical Sciences, The University of Sydney, Australia 2006;;6. 6Sydney Mass Spectrometry, The University of Sydney, Australia 2006
Abstract:
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  • Highlights
    • •Protein N-glycosylation is essential for nitrate reductase (Nap) activity in C. jejuni.
    • •Removal of N-glycosylation results in a metabolic switch from Asp to Pro uptake.
    • N-glycosylation is required for optimal chemotaxis towards several substrates.
    • •Loss of N-glycosylation reduces survival following temperature and osmotic shock.
    Keywords:N-Glycosylation  Glycoprotein Pathways*  Bacteria  Virulence  Microbiology  Bacterial pathogenesis  Stress response
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