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Quantitative Proteomics of the 2016 WHO Neisseria gonorrhoeae Reference Strains Surveys Vaccine Candidates and Antimicrobial Resistance Determinants
Institution:3. From the 3Department of Pharmaceutical Sciences, College of Pharmacy, Oregon State University, Corvallis, Oregon;;4. 4Department of Reproductive Health and Research, World Health Organization, Geneva, Switzerland;;5. 5Vaccine and Gene Therapy Institute, Oregon Health and Science University, Beaverton, Oregon;;6. 6World Health Organization Collaborating Centre for Gonorrhoea and other Sexually Transmitted Infections, Department of Laboratory Medicine, Clinical Microbiology, Faculty of Medicine and Health, Örebro University, Örebro, Sweden
Abstract:
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  • Highlights
    • ?Quantitative proteomes of the 2016 WHO Neisseria gonorrhoeae reference strains.
    • ?Novel gonorrhea vaccine candidates and potential global proteomic AMR markers.
    • ?First large-scale proteomic profiling of gonorrhea vaccine candidates and AMR.
    • ?A reference proteomics databank for gonococcal vaccine and AMR research endeavors.
    Keywords:Absolute Quantification  Bacteria  Pathogens  Membranes  Drug Resistance  Antibiotics  Gonorrhea  Neisseria gonorrhoeae  TMT  Vaccine
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