Why Glycosylation Matters in Building a Better Flu Vaccine |
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| Institution: | Dept. of Biochemistry, Boston University School of Medicine, Boston, MA 02118 |
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| Abstract: |  Download : Download high-res image (59KB)Download : Download full-size imageHighlights- •Glycosylation is not currently considered in flu vaccine design.
- •Glycosylation influences on immunodominance are not well understood.
- •Identification of site-specific glycosylation using mass spectrometry has matured.
- •New methods are needed to quantify site-specific glycosylation for vaccine design.
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| Keywords: | Glycoproteomics glycoprotein structure viruses glycoproteins clinical proteomics influenza A virus |
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