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Proteomic Analysis of Baboon Cerebral Artery Reveals Potential Pathways of Damage by Prenatal Alcohol Exposure,

Institution:	3. Department of Pharmacology, College of Medicine, University of Tennessee Health Science Center, 71 S. Manassas St., #205, Memphis, TN, 38103;;4. Proteomics Core, University of Tennessee Health Science Center, 71 S. Manassas St., #110, Memphis, TN, 38103;;5. Molecular Bioinformatics Core, University of Tennessee Health Science Center, 71 S. Manassas St., #110, Memphis, TN, 38103

Abstract:	Download : Download high-res image (105KB) Download : Download full-size image Highlights •We studied mid-pregnancy alcohol exposure and baboon fetal cerebral artery. •238 proteins differed between control and alcohol-exposed fetuses near-term. •Proteins of metabolic pathways represented one of the major targets of alcohol. •Alcohol effect on the development of fetal brain vessels is persistent.

Keywords:	Animal Models Pharmacology Physiology Pregnancy Cardiovascular Function or Biology Mass Spectrometry Mitochondria Function or Biology Networks Alcohol in Utero Binge Drinking Fetal Alcohol Syndrome and Spectrum Disorders Maternal Drinking Prenatal Alcohol Exposure
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