Review: The roles and functions of glutamine on intestinal health and performance of weaning pigs |
| |
| Institution: | 1. Hunan International Joint Laboratory of Animal Intestinal Ecology and Health, Laboratory of Animal Nutrition and Human Health, College of Life Sciences, Hunan Normal University, 36 Lushan Road, Changsha 410081, People’s Republic of China;2. Tropical Crops Genetic Resources Institute, Chinese Academy of Tropical Agricultural Sciences, 4 West Xueyuan Road, Haikou 571101, People’s Republic of China;3. Hunan Provincial Key Laboratory of Animal Nutritional Physiology and Metabolic Process; National Engineering Laboratory for Pollution Control and Waste Utilization in Livestock and Poultry Production, Institute of Subtropical Agriculture, Chinese Academy of Sciences, 644 Yuanda 2nd Road, Changsha 410125, People’s Republic of China;4. Academician Workstation of Changsha Medical University, 1501 Leifeng Road, Changsha 410219, People’s Republic of China |
| |
| Abstract: | The gut is composed of a single layer of intestinal epithelial cells and plays important roles in the digestion and absorption of nutrients, immune and barrier functions and amino acid metabolism. Weaning stress impairs piglet intestinal epithelium structural and functional integrities, which results in reduced feed intake, growth rates and increased morbidity and mortality. Several measures are needed to maintain swine gut development and growth performance after weaning stress. A large body of evidence indicates that, in weaning piglets, glutamine, a functional amino acid, may improve growth performance and intestinal morphology, reduce oxidative damage, stimulate enterocyte proliferation, modulate cell survival and death and enhance intestinal paracellular permeability. This review focuses on the effects of glutamine on intestinal health in piglets. The aim is to provide evidentiary support for using glutamine as a feed additive to alleviate weaning stress. |
| |
| Keywords: | swine weaning stress functional amino acid barrier function epithelial cell renewal |
| 本文献已被 ScienceDirect 等数据库收录！ |
|
