Small-protein Enrichment Assay Enables the Rapid,Unbiased Analysis of Over 100 Low Abundance Factors from Human Plasma |
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| Affiliation: | 3. 3Charles Perkins Centre, School of Life and Environmental Sciences, University of Sydney, Sydney, Australia |
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| Abstract: |  Download : Download high-res image (114KB)Download : Download full-size imageHighlights- •Development of a method for low-abundance small protein analysis in human plasma.
- •Deep proteome profiling demonstrated unbiased identification of diverse factors.
- •Method enabled identification of a novel human plasma protein C5ORF46.
- •Analysis of intermittent fasting response showed changes in iron regulation.
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| Keywords: | Serum/Plasma* Plasma or serum analysis Hormones* Chromatography Insulin resistance chemokine hepcidin insulin intermittent fasting |
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