Primary Human Natural Killer Cells Retain Proinflammatory IgG1 at the Cell Surface and Express CD16a Glycoforms with Donor-dependent Variability期刊界 All Journals 搜尽天下杂志传播学术成果专业期刊搜索期刊信息化学术搜索

Primary Human Natural Killer Cells Retain Proinflammatory IgG1 at the Cell Surface and Express CD16a Glycoforms with Donor-dependent Variability

Affiliation:	3. Roy J. Carver Department of Biochemistry, Biophysics & Molecular Biology, Iowa State University, Ames IA 50011;4. Office of Biotechnology, Protein Facility, Iowa State University, Ames IA 50011;5. Department of Biochemistry and Molecular Biology, University of Georgia, Athens 30602;6. Complex Carbohydrate Research Center, University of Georgia, Athens 30602

Abstract:	Download : Download high-res image (134KB) Download : Download full-size image Highlights •Enough CD16a from NK cells can be isolated from a single donor following apheresis. •NK cell CD16a shows variability between different donors. •NK cells preferentially bind IgG1 that lacks core fucosylation.

Keywords:	glycoproteomics immunology glycoprotein secretion post-translational modifications membranes CD16 Fc gamma receptor immunoglobulin G
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