Microfabricated nerve–electrode interfaces in neural prosthetics and neural engineering |
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| Authors: | Yong-Ak Song Ahmed MS Ibrahim Amr N Rabie |
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| Institution: | 1. Division of Engineering , New York University Abu Dhabi (NYUAD) , Abu Dhabi , UAE;2. Department of Chemical and Biomolecular Engineering , Polytechnic Institute of New York University , Brooklyn , NY , USA;3. Divisions of Plastic Surgery and Otolaryngology , Beth Israel Deaconess Medical Centre , Boston , MA , USA;4. Harvard Medical School , Boston , MA , USA;5. Department of Otolaryngology , Ain Shams University , Cairo , Egypt |
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| Abstract: | Neural interfaces and implants are finding more clinical applications and there are rapid technological advances for more efficient and safe design, fabrication and materials to establish high-fidelity neural interfaces. In this review paper, we highlight new developments of the microfabricated electrodes and substrates with regard to the design, materials, fabrication and their clinical applications. There is a noticeable trend towards integration of microfluidic modules on a single neural platform. In addition to the microelectrodes for neural recording and stimulation, microfluidic channels are integrated into a nerve–electrode interface to explore the rich neurochemistry present at the neural interface and exploit it for enhanced electrochemical stimulation and recording of the central and peripheral nervous system. |
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| Keywords: | neural prosthetics neural implant neural engineering microfabrication MEMS microelectrode array |
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