Synthesis of 1-hydroxyalkyl-3-substituted ureas and thioureas as a substrates for alcohol dehydrogenase] |
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Authors: | O N Leonov V M Shcherbakov V M Devichenski? L Iu Kriukova E A Vorontsov S L Kuznetsov L N Kriukov |
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Affiliation: | Institute of Biological Medicine, ul. Akademika Oparina 4, Mascow, 117815 Russia. |
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Abstract: | A series of 1-(2-hydroxyethyl)- and 1-(3-hydroxyethyl)-3-substituted ureas and thioureas were synthesized. 1-(3-Hydroxyethyl)-3-acylthioureas were shown to be specific substrates for alcohol dehydrogenase in vitro. |
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